Picking LOX to find antibodies
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چکیده
منابع مشابه
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متن کاملFailure to find C1q-binding material and anti-IgG antibodies in ankylosing spondylitis.
C1q-binding immune complexes (C1C), anti-IgG antibodies (anti-IgG Ab), and complement levels were investigated in the serum of 37 patients with ankylosing spondylitis (AS). In all these studies the mean levels observed in patients with AS were similar to those in 31 normal subjects. Moreover, no significative difference in either CIC or anti-IgG Ab levels was observed when the patients were cla...
متن کاملPicking pockets to fuel antimicrobial drug discovery.
The inhibition of essential enzymes in microbial pathogens offers a route to treatment of infectious diseases. However, although the biology of the organism dictates a need for a particular enzyme activity, this does not necessarily mean that the enzyme is a good drug target. The chemistry of the active site (size, shape and properties) determines the likelihood of finding a molecule with the r...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2014
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri3764